Virol . Erik Larsson and Jonas Blomberg Ann - Catrin Andersson

ERV3 and related sequences in humans: structure and RNA expression.

The ERV3 locus at chromosome 7q11 is a much studied human endogenous retroviral (HERV) sequence, owing to an env open reading frame (ORF) and placental RNA and protein expression. An analysis of the human genome demonstrated that ERV3 is one of a group of 41 highly related elements (ERV3-like HERVs) which use proline, isoleucine, or arginine tRNA in their primer binding sites. In addition to el...

A human protein atlas for normal and cancer tissues based on antibody proteomics.

Antibody-based proteomics provides a powerful approach for the functional study of the human proteome involving the systematic generation of protein-specific affinity reagents. We used this strategy to construct a comprehensive, antibody-based protein atlas for expression and localization profiles in 48 normal human tissues and 20 different cancers. Here we report a new publicly available datab...

Complement-Opsonized HIV-1 toward Dendritic Cells Exposed to Impaired NK Cell Activation and Chemotaxis

Inactivation of TGFb receptors in stem cells drives cutaneous squamous cell carcinoma

Patrizia Cammareri1,*, Aidan M. Rose2,*, David F. Vincent1,*, Jun Wang3, Ai Nagano3, Silvana Libertini1, Rachel A. Ridgway1, Dimitris Athineos1, Philip J. Coates4, Angela McHugh2, Celine Pourreyron2, Jasbani H.S. Dayal2, Jonas Larsson5, Simone Weidlich6, Lindsay C. Spender2, Gopal P. Sapkota6, Karin J. Purdie7, Charlotte M. Proby2, Catherine A. Harwood7, Irene M. Leigh2,7, Hans Clevers8, Nick B...

Review – Sexual Medicine Update on Phosphodiesterase (PDE) Isoenzymes as Pharmacologic Targets in Urology: Present and Future

Stefan Ückert *, Petter Hedlund , Karl-Erik Andersson , Michael C. Truss , Udo Jonas , Christian G. Stief c Hannover Medical School, Department of Urology, Hannover 30625, Germany b Lund University Hospital, Department of Clinical Pharmacology, Lund, Sweden c Ludwig-Maximilians-University, Department of Urology, Academic Hospital Grosshadern, Munich, Germany d IPF, PharmaCeuticals GmbH, Urologi...